Formación académica
Trayectoria profesional y docente
Distinciones y premios
Reingreso vigente en el Sistema Nacional de Investigadores (SNI) Convocatoria 2023-2027. Investigador Nacional Nivel II. 2023
Asesora del Grupo Estudiantil iGEM (International Genetically Engineered Machine) 2003 - Actualidad
Proyecto de Investigación (No. UIN23509). Fondeado por la Gerencia de investigación y Proyectos Convocatoria 2023, UDEM
Reingreso vigente en el Sistema Nacional de Investigadores (SNI) Mexicanos en el Extranjero. Convocatoria 2019-2022. Investigador Nacional Nivel II. 2020
Reingreso vigente en el Sistema Nacional de Investigadores (SNI) Mexicanos en el Extranjero. Convocatoria 2019-2022. Investigador Nacional Nivel II. 2018
Travel Award Marine Biological Laboratory 2016
Obtención del Premio “Early Career Investigator Travel Award” Keystone Co, USA 2016
Premio al Mejor Trabajo University of Texas Medical Branch 2014
Beca Postdoctoral University of Texas Medical Branch y la Escuela de Graduados en Ciencias Biomédicas 2010
Beca del Consejo Nacional de Ciencia y Tecnología, CONACYT Galveston Texas, USA 2009
Reconocimiento como Estudiante distinguido del Programa de Doctorado en Ciencias Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México 2004
Mención Honorífica Maestría en Ciencias con Orientación en Morfología 2002
Ganadora de una beca Center of Neurobiology, UNAM, Juriquilla Querétaro, México 2001
Publicaciones
Jackson N, Guerrero-Munoz MJ, Castillo-Carranza DL., The prion-like transmission of tau oligomers via exosomes. Front Aging Neurosci. 2022
Castillo-Carranza DL., A toxic subset of soluble α-synuclein species in dementia with Lewy body. Brain Commun. 2020
Gerson JE, Farmer KM, Henson N, Castillo-Carranza DL, Carretero-Murillo M, Sengupta M, Barret A, Kayed R. Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy. Molecular Neurodegeneration, 2018.
Castillo-Carranza DL, Guerrero-Muñoz MJ, Sengupta U, Gerson JE, Kayed R. α-synuclein oligomers induce a unique toxic tau strain. Biological Psychiatry 2018.
Castillo-Carranza DL, Nilson AN, Van Skike CE, Jahrling JB, Patel K, Garach P, Gerson JE, Sengupta U, Abisambra J, Nelson P, Troncoso J, Ungvari Z, Galvan V, Kayed R. Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer's Disease and Related Tauopathies. Aging Dis. 2017
Shafiei SS, Guerrero-Muñoz MJ, Castillo-Carranza DL. Tau Oligomers: Cytotoxicity, Propagation, and Mitochondrial Damage. Front Aging Neurosci. 2017
Sengupta U, Portelius E, Hansson O, Farmer K, Castillo-Carranza D, Woltjer R, Zetterberg H, Galasko D, Blennow K, Kayed R. Tau oligomers in cerebrospinal fluid in Alzheimer's disease. Ann Clin Transl Neurol. 2017.
Nilson AN, English KC, Gerson JE, Whittle TB, Crain CN, Xue J, Sengupta U, Castillo-Carranza DL, Zhang W, Gupta P, Kayed R. Tau oligomers associate with inflammation in the brain and retina of tauopathy mice and in neurodegenerative diseases. JAD 2017.
Gerson JE, Castillo-Carranza DL, Sengupta U, Bodani R, Prough DS, DeWitt D, Hawkins BE, Kayed R. Tau oligomers derived from Traumatic Brain Injury cause cognitive impairment and accelerate onset of pathology in Htau mice. Neurotrauma. 2016 Jan 5.
Presencia en Congresos
Castillo- Carranza DL (Abril, 2019). Ponencia: “Anticuerpos Conformacionales con Potencial Terapeutico”, Centro de Investigacion y Desarrollo en Ciencias de la Salud, UANL.
Castillo-Carranza DL (Spring 2017). Titulo: “Alzheimer’s disease: A prion-like disorder”. BIO425 Research Seminar Series.
Castillo-Carranza DL, (2016). Development of Alzheimer’s/Dementia Research Capacity and Center at HU. Researcher’s Informational Forum, Hampton University.
Castillo-Carranza DL. (2015). Potential role of exosomal tau and alpha-synuclein oligomers in cell toxicity and spreading pathology in PD and DLB. The Society for Neuroscience.
Castillo-Carranza DL (2015). Intersection of α-Synuclein seeds and Tau augment propagation and neurotoxicity. George P. and Cynthia Mitchell center for neurogenerative disease, seminar series, UTMB, Galveston TX.